Endocrine Abstracts

Cushing disease (CD) is a rare affection due to an ACTH secreting pituitary adenoma with a hypercorticism as main consequence.The aim of this study was to assess glucose tolerance anomalies in CD.Patients: Twenty-one patients with a diagnosed CD were included; The majority of them (77.3%; n=17) were female. Mean age was 34.2 (19–54 years) and mean BMI 31.9 kg/m2 (25.9–43.7). Mean progression period of ...

Achieving glycemic targets is crucial in the management of diabetes mellitus. Insulin is the most effective hypoglycemic treatment for diabetes but its use can be associated with a risk of hypoglycemia.The aim of this study is to specify risk factors of hypoglycemia in insulin-treated patients.Patients and methods: This transversal study included 69 patients. They were females in 49.4% of cases (n=41). Mean age was 52 year...

Prolactinoma is a pituitary adenoma producing prolactin. Central hypogonadism is a major consequence of prolactinoma leading, in women, to menstrual troubles and infertility. The aim of this study was to specify gynecological characteristics of prolactinomas.Patients: This retrospective study included 28 female patients with prolactinoma. Mean age at diagnosis was 35.46 years (ext: 20–78). Mean serum prolactin level was 3442.4 ng/ml (ext: 31.9–...

Introduction: Type 1 diabetic women have generally more menstrual disorders than healthy women.Objectives: Identify the main mechanisms responsible of menstrual disorders in type1 diabetic women.Patients and methods: We conducted a comparative transversal study including 70 patients with type 1 diabetes: Thirty-three having menstrual disorders (group M) and 37 with regular menses (control group T).We compared...

Introduction: Generously supported by IPSEN)-->Prolactinoma is the commonest pituitary adenoma. The aim of this study was to compare clinical, biological and radiological characteristics in microprolactinoma and macroprolactinoma.Patients: This retrospective study included 33 patients with prolactinoma. The tumor was a microadenoma (<1 cm) in 27.3% (n=9) and a macroadenoma in 72.7% (n=24) ...